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flhB [2019-04-15 18:58:19]
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flhB [2019-04-15 18:58:19]

part of the flagellar type III export apparatus (flagellar Type III secretion system)
Locus
BSU16380
Isoelectric point
9.77
Molecular weight
40.94 kDa
Protein length
360 aa Sequence Blast
Gene length
1083 bp Sequence Blast
Function
export of flagellum components
Product
part of the flagellar type III export apparatus
Essential
no
Synonyms

Genomic Context

      
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Categories containing this gene/protein

Gene

Coordinates
1,706,599 1,707,681

Phenotypes of a mutant

  • no secretion of FlgM, permanent inhibition of SigD PubMed
  • The protein

    Protein family

  • type III secretion exporter family (according to Swiss-Prot)
  • Localization

  • cell membrane, 4 transmembrane helices PubMed
  • Expression and Regulation

    Operons

    Description

    Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon
  • SigD: sigma factor, PubMed, in SigD regulon
  • Regulatory mechanism

  • Spo0A: repression, in Spo0A regulon
  • CodY: repression, in CodY regulon
  • DegU: regulation, in DegU regulon
  • SwrA: activation, in SwrA regulon
  • Regulation

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    Description

    Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon
  • SigD: sigma factor, PubMed, in SigD regulon
  • Regulatory mechanism

  • Spo0A: repression, in Spo0A regulon
  • SwrA: activation, in SwrA regulon
  • CodY: repression, in CodY regulon
  • DegU: repression, in DegU regulon
  • Regulation

  • expression during spore germination is strongly reduced under conditions of osmotic stress PubMed
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    Biological materials

    Mutant

  • BKE16380 (flhB::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CTGCAGGTCAACTCTAAGCT, downstream forward: _UP4_TGAATTTTTCGATTTAAAAG
  • BKK16380 (flhB::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CTGCAGGTCAACTCTAAGCT, downstream forward: _UP4_TGAATTTTTCGATTTAAAAG
  • References

    Reviews

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    Original publications

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